Redox Regulation of Stem and Progenitor Cells
نویسندگان
چکیده
منابع مشابه
Redox Regulation in Cancer Stem Cells
CD44 was identified as a cell surface marker for cancer stem cells (CSCs) in various epithelial tumor. However, function-based evidence to support the role of CD44 in CSCs was not known. We found that expression of CD44, in particular variant forms of CD44 (CD44v), suppresses reactive oxygen species (ROS) levels by promoting the synthesis of reduced glutathione(GSH), a primary intracellular ant...
متن کاملNutritional regulation of stem and progenitor cells in Drosophila.
Stem cells and their progenitors are maintained within a microenvironment, termed the niche, through local cell-cell communication. Systemic signals originating outside the niche also affect stem cell and progenitor behavior. This review summarizes studies that pertain to nutritional effects on stem and progenitor cell maintenance and proliferation in Drosophila. Multiple tissue types are discu...
متن کاملA Review of the Factors Affecting the Proliferation of Neural Stem and Progenitor Cells
Neural stem cells are undifferentiated cells that are located in limited areas of central nervous system. These cells have proliferation and self-renew ability and can be differentiated into neurons and glial cells. Mature nerve cells do not have proliferative ability; and due to the limited number of nerve stem cells, injuries to the nervous system are not recoverable. The purpose of this revi...
متن کاملIsolation and Differentiation of Neural Stem/Progenitor Cells From Subventricular Zone of One Adult Rat
Introduction: In adult mammalian brain, neural stem cells are isolated from both the dentate gyrus and subventricular zone. This study aimed to isolate neural stem cells from adult rat subventricular zone and differentiate them into neurons and astrocytes. Methods: In this study, the whole brain was removed after full anesthesia and creating cervical dislocation. Under a microscope, subv...
متن کاملHEMATOPOIESIS AND STEM CELLS CD1d expression on and regulation of murine hematopoietic stem and progenitor cells
In the present study, surface CD1d, which is involved in immune cell interactions, was assessed for effects on hematopoiesis. Mouse BM hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) express CD1d. The numbers and cycling status of HPCs in the BM and spleen of different strains of cd1d / mice were enhanced significantly, suggesting that CD1d is a negative regulator of H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2008
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2008.2141